...the mechanisms of the biochemical processes happening in enzymes, photoreceptor proteins and protein complexes. We apply modern supercomputer molecular modeling tools including combined quantum mechanics/molecular mechanics, quantum chemical methods, molecular...
...Hansenula polymorpha was created, which allowed molecular genetic studies with this yeast species. The behavior of replicative and integrative plasmids in H. polymorpha cells was studied. Particularly, recombinational rearrangements of...
...Yury A. Nikolaev Dr. Sci. (Biology) Head of Laboratory INMI, room 407 +7 (495) 135-01-80 nikolaevya@mail.ru...
...Live Cells Using Pair of Red Fluorescent Proteins. -Theranostics, 2012, v. 2, N 2, pp. 215-226. (DOI:10.7150/thno.3885) B. Grigorenko, A. Savitsky, I. Topol, S. Burt, A.Nemukhin. Ground-State Structures and Vertical...
...in CHO cells. Coagulation factor production for the treatment of hemophilia Development of highly efficient cell lines, producing factor VIII as a full-length and B-domain deleted protein. Development of original...
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...communities both in formation and functioning of the modern biosphere on our planet. Concurrently with pure microbial cultures, interactions between microorganisms in biocoenoses, where metabolic and syntrophic relationships play a...
...for early interaction with host cell, such as herpes simplex virus and cytomegalovirus. The compound demonstrated efficacy in several preclinical animal models, including a rabbit model of herpes simplex epithelial...
...system of mechanisms of cooperation between Russia and the EU in science and technology and innovation in support of the task force TaskForce in food and agricultural biotechnology. Development of...
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...heterothallism and dimorphism in Mucorales Development of biotechnological foundations for the synthesis of biologically active lipids, using producers of pharmacologically active essential PUFAs Development of new medications, based on fungal...
...and purification of leghemoglobin and metleghemoglobin reductase – the enzyme that supports it in physiologically active reduced state Study of interaction of erythrocyte hemoglobin (Hb) with reactive oxygen and nitrogen...
...business communities, as well as held more than 100 infodays, seminars, trainings and webinars. In the framework of Symposium the meetings of the EU-Russia Working Group “AgroBioFood” are held. NCP...
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...publications Karginov AV, Alexandrov AI, Kushnirov VV, Agaphonov MO. Perturbations in the Heme and Siroheme Biosynthesis Pathways Causing Accumulation of Fluorescent Free Base Porphyrins and Auxotrophy in Ogataea Yeasts. J...
...“bioelectrocatalysis” of oxidoreductases. He is the author of 19 patents and more that 160 publications in refereed journals. Scientific interests, priorities: physico-chemical study of oxidoreductases and their application in biotechnology;...
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